Publications
​
Jiachen Z, Paul Kwong Hang T, Kenneth Kak Yuen W, Vincent Chi Hang L*. Pathological role of methionine in the initiation and progression of biliary atresia. Front Pediatr. 2023 Sep 12;11:1263836. doi: 10.3389/fped.2023.1263836. PMID: 37772039; PMCID: PMC10522914.
​
​
Ye Y, Lui VCH, Babu RO, Wu Z, Wu W, Chung PHY, Wong KKY, Wang B, Tam PKH*. Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids. PLoS One. 2023 Mar 30;18(3):e0283737. doi: 10.1371/journal.pone.0283737. PMID: 36996081; PMCID: PMC10062558.
​
​
Fung AC, Ye HY, Lau TW, Lui VC, Wong KK*. Does the Choice of Suture Materials Affect the Vas Deferens after Hernia Ring Closure in Inguinal Hernia Surgery: An Experimental Study in Rats. J Pediatr Surg. 2023 Jul;58(7):1301-1305. doi: 10.1016/j.jpedsurg.2023.01.056. Epub 2023 Feb 14. PMID: 36894446.
​
​
Hei Ha JL, Hang Lui VC, Hang Tam PK*. Embryology and anatomy of Hirschsprung disease. Semin Pediatr Surg. 2022 Dec;31(6):151227. doi: 10.1016/j.sempedsurg.2022.151227. Epub 2022 Nov 16. PMID: 36417785.
​
​
Li J, Chu J, Lui VCH, Chen S, Chen Y, Tam PKH*. (2022) Bioengineering Liver Organoids for Diseases Modelling and Transplantation. Bioengineering 2022, 9, 796.
​
​
Ye Y, Lui VCH, Tam PKH. (2022) Pathogenesis of Choledochal Cyst: Insights from Genomics and Transcriptomics. Genes 2022, 13, 1030.
​
​
Liu XL, Lui VCH, Wang H, Ye M, Fa R, Xie XH, Li L, Jin ZW. (2022) Temporal and spatial development of intestinal smooth muscle layers of human embryos and fetuses. J Dev Orig Health Dis. 2022 Aug 4;1-9..
​
​
Zhang R, Su L, Fu M, Wang Z, Tan L, Chen H, Lin Z, Tong Y, Ma S, Ye R, Zhao Z, Wang Z, Chen W, Yu J, Zhong W, Zeng J, Liu F, Chai C, Guan X, Liu T, Liang J, Zhu Y, Gu X, Zhang Y, Lui VCH, Tam PKH, Lamb JR, Wen Z, Chan Y, Xia H. (2022) CD177+ cells produce neutrophil extracellular traps that promote biliary atresia. J Hepatol. 77:1299–1310
Lyn H, Ye Y, Lui VCH, Wu W, Chung PHY, Wong KKY, Li H-W, Wong MS, Tam PKH, Wang B. (2022) Plasma amyloid-beta levels correlated with impaired hepatic functions: an adjuvant biomarker for the diagnosis of Biliary Atresia. Front. Surg., 05 September 2022. Sec. Pediatric Surgery.
​
​
Lyn H, Ye Y, Lui VCH, Wang B. (2022) Reducing fibrosis progression of biliary atresia by continuous administration of aducanumab at low dose: A potential treatment. Medical Hypotheses 2022; 165, 110901.
​
​
Ye Y, Lui VCH, Tam P.K.H. (2022) Pathogenesis of Choledochal Cyst: Insights from Genomics and Transcriptomics. Genes (Basel) 2022 Jun; 13(6): 1030. Published online 2022 Jun 8. doi: 10.3390/genes13061030 PMCID: PMC9223186
​
​
He L, Chung PHY, Lui VCH, Tang CSM, Tam PKH. (2022) Current Understanding in the Clinical Characteristics and Molecular Mechanisms in Different Subtypes of Biliary Atresia. Int. J. Mol. Sci. 2022, 23, 4841.
​
​
Chung PHY, Babu RO, Wu Z, Wong KKY, Tam PKH, Lui VCH. (2022) Developing biliary atresia-like model by treating human liver organoids with polyinosinic:Polycytidylic acid [Poly (I:C)]. (2022). Curr. Issues Mol. Biol. 2022, 44(2), 644-653.
​
​
Lui VCH, Hui KPY, Babu RO, Yue H, Chung PHY, Tam PKH, Chan MCW, Wong KKY. Human liver organoid derived intra-hepatic bile duct cells support SARS-CoV-2 infection and replication. Sci Rep. 2022 Mar 30;12(1):5375. doi: 10.1038/s41598-022-09306-6.
​
​
Menon S, Lui VCH, Tam PKH. Comparison of computational tools for differential gene expression analysis of RNA sequencing and single-cell RNA sequencing data. European Journal of Biomedical and Pharmaceutical Sciences. 2022 March 26;9(4):1-9. https://www.ejbps.com/ejbps/abstract_id/8681.
​
​
Chung PHY, Babu RO, Wu Z, Wong KKY, Tam PKH, Lui VCH*. Developing biliary atresia-like model by treating human liver organoids with polyinosinic:Polycytidylic acid [Poly (I:C)]. Curr. Issues Mol. Biol. 2022 January;44(2):644-653. doi:10.3390/cimb44020045.
​
​
Menon S, Lui VCH, Tam PKH. Statistical approach for Predicting Genome Architecture and the major challenges. World Journal of Advanced Research and Reviews. 2022 January;13(1):433-445. doi: 10.30574/wjarr.2022.13.1.0022. https://wjarr.com/content/statistical-approach-predicting-genome-architecture-and-major-challenges.
​
​
Lendahl U, Lui VCH, Chung PHY, Tam PKH. Biliary Atresia – emerging diagnostic and therapy opportunities. EBioMedicine. 2021 Dec;74:103689. doi: 10.1016/j.ebiom.2021.103689. Epub 2021 Nov 12.
​
​
Menon S, Lui VCH, Tam PKH. A step-by-step work flow of single cell RNA sequencing data analysis. International Journal for Scientific Research & Development. 2021;9(6):1-13.
Menon S, Lui VCH, Tam PKH. Bioinformatics methods for identifying hirschsprung disease genes. International Journal for Research in Applied Science & Engineering Technology. 2021 July;9(7).
He L, Ip DKM, Tam G, Lui VCH, Tam PKH, Chung PHY. Biomarkers for the diagnosis and post-Kasai portoenterostomy prognosis of biliary atresia: a systematic review and meta-analysis. Sci Rep. 2021 Jun 3;11(1):11692. doi: 10.1038/s41598-021-91072-y. PMID: 34083585.
​
Fu M, Tan L, Lin Z, Lui VCH, Tam PKH, Lamb JR, Zhang Y, Xia H, Zhang R, Chen Y. Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia. Clin Sci (Lond). 2021 Apr 16;135(7):865-884. doi: 10.1042/CS20201366.
​
Menon S, Ramer-Tait A, Piramanagakam S, Lui VCH, Tam PKH. Bisulphite seq data reveals host-microbiota interaction in germfree and conventional mice. International Journal of Bioinformatics and Biological Sciences. 2021 March 15;9(1):1-8. https://intbioinformaticsjr.com/Journal/downloadIssue/id/NDg2NQ==/file/pdf.
​
​
Cheung Y, Wu Z, Garcia-Barcelo MM, Tam PKH, Ma ACH, Lui VCH. Deletion of interleukin enhancer binding factor 2 (ILF2) resulted in defective biliary development and bile flow blockage. Journal of Pediatric Surgery. 2021 Feb;56(2):352-359. doi: 10.1016/j.jpedsurg.2020.06.032. Epub 2020 Jun 27. PMID: 32709532.
​
​
Babu RO, Lui VCH, Chen Y, Yiu RSW, Ye Y, Niu B, Wu ZL, Zhang RZ, Yu MON, Chung PHY, Wong KKY, Xia H, Zhang MQ, Wang B, Lendahl U, Tam PKH. Beta-amyloid deposition around liver bile ducts as a novel pathobiological and diagnostic feature of biliary atresia. Journal of Hepatology. 2020 Dec;73(6):1391-1403. doi: 10.1016/j.jhep.2020.06.012. Epub 2020 Jun 16.
​
​
Wei X, Ma W, Gu H, Liu D, Luo W, Bai Y, Wang W, Lui VCH, Yang P, Yuan Z. Transamniotic mesenchymal stem cell therapy for neural tube defects preserves neural function through lesion-specific engraftment and regeneration. Cell Death Dis. 2020 Jul; 11(7): 523. Published online 2020 Jul 13. doi: 10.1038/s41419-020-2734-3.
​
​
Zhang K, Lui VCH, Chen Y, Lok CN, Wong KKY. Delayed application of silver nanoparticles reveals the role of early inflammation in burn wound healing. Sci Rep. 2020 Apr 14;10(1):6338. doi: 10.1038/s41598-020-63464-z.
​
​
Zhang R, Lin Z, Fu M, Guan X, Yu J, Zhong W, Zeng J, Lui VCH, Tam PKH, Lamb JR, Xia H, Chen Y. The Role of Neonatal Gr-1+ Myeloid Cells in a Murine Model of Rhesus-Rotavirus-Induced Biliary Atresia. Am J Pathol. 2018 Nov;188(11):2617-2628. doi: 10.1016/j.ajpath.2018.07.024.
​
​
Qian C, Wu ZL, Ng RCL, Garcia-Barceló MM, Yuan ZW, Wong KKY, Tam PKH, Lui VCH. Conditional deletion of platelet derived growth factor receptor alpha (Pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice. Cell Death Differ. 2019 Aug;26(8):1396-1410. doi: 10.1038/s41418-018-0216-2. Epub 2018 Oct 15. PMID: 30323271.
​
​
Zhang RZ, Zeng XH, Lin ZF, Fu M, Tong YL, Lui VCH, Tam PKH, Lamb JR, Xia HM, Chen Y. Downregulation of Hes1 expression in experimental biliary atresia and its effects on bile duct structure. World J Gastroenterol. 2018 Aug 7;24(29):3260-3272. doi: 10.3748/wjg.v24.i29.3260.
​
​
Hsu JSJ, So M, Tang CSM, Karim A, Porsch RM, Wong C, Yu M, Yeung F, Xia H, Zhang R, Cherny SS, Chung PHY, Wong KKY, Sham PC, Ngo ND, Li M, Tam PKH, Lui VCH, Garcia-Barcelo MM. De novo mutations in Caudal Type Homeo Box transcription Factor 2 (CDX2) in patients with persistent cloaca. Hum Mol Genet. 2018 Jan 15;27(2):351-358. doi: 10.1093/hmg/ddx406.
​
​
Qian C, Wong CWY, Wu Z, He Q, Xia H, Tam PKH, Wong KKY, Lui VCH. Stage specific requirement of Platelet-derived growth factor receptor-α in embryonic development. PLoS One. 2017 Sep 21;12(9):e0184473. doi: 10.1371/journal.pone.0184473.
​
​
Zhang R, Lin Z, Lui VCH, Wong KKY, Tam PKH, Lee P, Lok CN, Lamb JR, Chen Y, Xia H. Silver nanoparticle treatment ameliorates biliary atresia syndrome in rhesus rotavirus inoculated mice. Nanomedicine. 2017 Apr;13(3):1041-1050. doi: 10.1016/j.nano.2016.11.013. Epub 2016 Nov 25.
​
​