HKU develops a light-controlled nanomedicine for precise drug delivery to treat colorectal cancer

Dr. Wang Weiping, Assistant Professor of Dr. Li Dak-Sum Research Centre and Department of Pharmacology and Pharmacy, HKUMed, and Principal Investigator of the State Key Laboratory of Pharmaceutical Biotechnology, HKU, (second from left, front row) and his research team.

A research team from Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has developed a photo-responsive nanomedicine for light-controlled colorectal cancer therapy. The nanoparticles are simply made by self-assembly of a near-infrared dye and a prodrug. After intravenous injection, the nanoparticles can target colon tumours and release drugs to kill cancer cells upon light irradiation. This process can be in-situ monitored by in vivo imaging. The research has been published in Bioengineering & Translational Medicine (link to the publication), and a patent application has been filed based on this work.

Source:

Li Ka Shing Faculty of Medicine, The University of Hong Kong

Date: March 23, 2022

Topic: HKU develops a light-controlled nanomedicine for precise drug delivery to treat colorectal cancer

Link: https://www.med.hku.hk/en/news/press/20220323-light-controlled-nanomedicine-for-colorectal-cancer

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